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Microvasculitic paraproteinaemic polyneuropathy and B-cell lymphoma.

Abstract:

Microvasculitis may play a greater part in the pathogenesis of paraproteinaemic neuropathies than is generally recognised, producing tissue destruction by convergent immune and physical mechanisms. We present a patient with a clinical syndrome of mononeuritis multiplex and a circulating IgM lambda paraprotein, in whom bone marrow aspiration revealed a lymphoplasmacytoid lymphoma. Microvasculitic changes were present in the first nerve biopsy, and the second showed extensive destruction of neu...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Warren, JD More by this author
Jacobs, JM More by this author
Groves, MJ More by this author
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Journal:
Journal of the peripheral nervous system : JPNS
Volume:
8
Issue:
2
Pages:
100-107
Publication date:
2003-06-05
DOI:
EISSN:
1529-8027
ISSN:
1085-9489
URN:
uuid:3888ae70-b506-47c2-aa08-91c376fa4e75
Source identifiers:
373967
Local pid:
pubs:373967

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