Journal article icon

Journal article

The polypyrimidine tract binding protein is a monomer.

Abstract:

The polypyrimidine tract binding (PTB) protein is a potent regulator of alternative mRNA splicing. It also participates in other essential cellular functions, including translation initiation and polyadenylation. Several published reports have suggested that the protein forms a dimer in solution, a feature that has been widely incorporated into mechanistic models of protein function. However, recent studies have provided indications that full-length PTB is a monomer. Here we present new bioph...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1261/rna.2214405

Authors


Hernandez, H More by this author
Robinson, CV More by this author
Simpson, P More by this author
Matthews, S More by this author
Expand authors...
Journal:
RNA (New York, N.Y.)
Volume:
11
Issue:
12
Pages:
1803-1808
Publication date:
2005-12-05
DOI:
EISSN:
1469-9001
ISSN:
1355-8382
URN:
uuid:3883b7ce-5dce-42bc-acb8-7b870a0321b7
Source identifiers:
59429
Local pid:
pubs:59429

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP