Journal article
The architecture and ppGpp-dependent expression of the primary transcriptome of Salmonella Typhimurium during invasion gene expression.
- Abstract:
-
BACKGROUND: Invasion of intestinal epithelial cells by Salmonella enterica serovar Typhimurium (S. Typhimurium) requires expression of the extracellular virulence gene expression programme (ST(EX)), activation of which is dependent on the signalling molecule guanosine tetraphosphate (ppGpp). Recently, next-generation transcriptomics (RNA-seq) has revealed the unexpected complexity of bacterial transcriptomes and in this report we use differential RNA sequencing (dRNA-seq) to define the high-...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 735.6KB, Terms of use)
-
(Version of record, zip, 1.5MB, Terms of use)
-
- Publisher copy:
- 10.1186/1471-2164-13-25
Authors
Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
Ramachandran, V
Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- BMC genomics More from this journal
- Volume:
- 13
- Issue:
- 1
- Pages:
- 25
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
-
1471-2164
- ISSN:
-
1471-2164
Item Description
- Language:
-
English
- Keywords:
- UUID:
-
uuid:387b6127-b87c-4c67-99f1-1b18832e52d0
- Local pid:
-
pubs:411570
- Source identifiers:
-
411570
- Deposit date:
-
2013-11-16
Terms of use
- Copyright holder:
- Ramachandran et al
- Copyright date:
- 2012
- Notes:
- © 2012 Ramachandran et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record