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Pathological sympathoexcitation: how is it achieved?

Abstract:

AIM: Congestive heart failure (CHF) and obstructive sleep apnoea syndrome (OSAS) are both associated with an intense sympathoexcitation, including an increased muscle sympathetic nerve activity (MSNA). We have studied the firing characteristics of single vasoconstrictor fibres to the muscle vascular bed in CHF and OSAS patients, at rest and during transient sympathoexcitatory stimuli, to elucidate the mechanisms by which vasoconstrictor output is augmented in these conditions. RESULTS: The m...

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Acta physiologica Scandinavica
Volume:
177
Issue:
3
Pages:
405-411
Publication date:
2003-03-05
DOI:
EISSN:
1365-201X
ISSN:
0001-6772
URN:
uuid:387716fc-8b00-4367-abab-1aa29ab09b8b
Source identifiers:
269831
Local pid:
pubs:269831

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