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Journal article : Review

Manipulation of the microbiome in critical illness—probiotics as a preventive measure against ventilator-associated pneumonia

Abstract:

Objective:
To describe the possible modes of action of probiotics and provide a systematic review of the current evidence on the efficacy of probiotics to prevent ventilator-associated pneumonia (VAP) in critically ill patients.


Methods:
We conducted an unrestricted search of the English language medical literature. For each individual study, the relative risk of VAP was calculated using the reported primary outcome data.


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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/s40635-019-0238-1

Authors


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Role:
Author
ORCID:
0000-0003-2911-4549
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0001-5190-2395
NIAID NIH HHS More from this funder
Publisher:
Springer Publisher's website
Journal:
Intensive Care Medicine Experimental Journal website
Volume:
7
Issue:
S1
Article number:
37
Publication date:
2019-07-25
Acceptance date:
2019-03-07
DOI:
EISSN:
2197-425X
Pmid:
31346841
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1039690
Local pid:
pubs:1039690
Deposit date:
2020-11-06

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