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Journal article

Mathematical models of the electrical action potential of Purkinje fibre cells.

Abstract:

Early development of ionic models for cardiac myocytes, from the pioneering modification of the Hodgkin-Huxley giant squid axon model by Noble to the iconic DiFrancesco-Noble model integrating voltage-gated ionic currents, ion pumps and exchangers, Ca(2+) sequestration and Ca(2+)-induced Ca(2+) release, provided a general description for a mammalian Purkinje fibre (PF) and the framework for modern cardiac models. In the past two decades, development has focused on tissue-specific models with ...

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Publication status:
Published

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Publisher copy:
10.1098/rsta.2008.0283

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Journal:
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Volume:
367
Issue:
1896
Pages:
2225-2255
Publication date:
2009-06-05
DOI:
EISSN:
1471-2962
ISSN:
1364-503X
URN:
uuid:38227495-5377-496b-8699-ca38a1a9ccca
Source identifiers:
239181
Local pid:
pubs:239181

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