Journal article
Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection.
- Abstract:
-
The CD8+ T cell response to Epstein-Barr virus (EBV) is well characterized. Much less is known about the evolution of the CD4+ T cell response. Here we show that EBV stimulates a primary burst of effector CD4+ T cells and this is followed by a period of down-regulation. A small population of EBV-specific effector CD4+ T cells survives during the lifelong persistent phase of infection. The EBV-specific effector CD4+ T cells accumulate within a CD27+ CD28+ differentiation compartment during pri...
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- Publication status:
- Published
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- Publisher copy:
- 10.1084/jem.20022058
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Authors
Bibliographic Details
- Journal:
- Journal of experimental medicine
- Volume:
- 198
- Issue:
- 6
- Pages:
- 903-911
- Publication date:
- 2003-09-01
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- Source identifiers:
-
32457
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:32457
- UUID:
-
uuid:3804ffb5-3359-4afb-9e17-a78cffc1bf3c
- Local pid:
- pubs:32457
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2003
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