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Journal article

Treatment of severe ulcerative colitis

Abstract:

10-15% of patients with ulcerative colitis experience a severe episode of colonic inflammation that does not respond to mesalazine and oral corticosteroids. These patients require hospitalisation and treatment with intravenous corticosteroids. However, 25% of these patients do not respond to treatment. In these cases, intravenous cyclosporin is effective. Infliximab, an antibody against tumour necrosis factor α, is also beneficial. With these new treatment options, the colectomy rate in the a...

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Nederlands Tijdschrift voor Geneeskunde
Volume:
150
Issue:
1
Pages:
12-17
Publication date:
2006-01-07
ISSN:
0028-2162
Source identifiers:
191100
Language:
Dutch; Flemish
Pubs id:
pubs:191100
UUID:
uuid:37efb058-4d56-4818-8294-34492cb72224
Local pid:
pubs:191100
Deposit date:
2012-12-19

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