Journal article
COX-2 inhibitors and the heart: are all coxibs the same?
- Abstract:
-
The selective COX-2 inhibitors (coxibs) were originally developed to minimise the adverse effects of conventional non-steroidal anti-inflammatory drugs (NSAIDs) while maintaining the same analgesic and anti-inflammatory properties. Many large studies confirmed the improved gastric side effect profile of coxibs compared with non-selective NSAIDs; however, reports of increased cardiovascular morbidity and mortality followed, and the manufacturer Merck was forced to withdraw rofecoxib (Vioxx) fr...
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- Publisher copy:
- 10.1136/pgmj.2005.042234
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Authors
Bibliographic Details
- Journal:
- Postgraduate medical journal
- Volume:
- 82
- Issue:
- 966
- Pages:
- 242-245
- Publication date:
- 2006-04-01
- DOI:
- EISSN:
-
1469-0756
- ISSN:
-
0032-5473
- Source identifiers:
-
414606
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:414606
- UUID:
-
uuid:37dcfc54-4a03-4598-a81f-67ce1a7c2c8d
- Local pid:
- pubs:414606
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2006
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