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Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis

Abstract:: Cellular decision-making is mediated by a complex interplay of external stimuli with the intracellular environment, in particular transcription factor regulatory networks. Here we have determined the expression of a network of 18 key haematopoietic transcription factors in 597 single primary blood stem and progenitor cells isolated from mouse bone marrow. We demonstrate that different stem/progenitor populations are characterized by distinctive transcription factor expression states, and thro...
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APA Style

Moignard, V., MacAulay, I., Swiers, G., Buettner, F., Schütte, J., Calero-Nieto, F., Kinston, S., Joshi, A., Hannah, R., Theis, F., Jacobsen, S. E., De Bruijn, M., & Göttgens, B. (2013). Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis. Nature Cell Biology, 15(4), 363–372.

MLA Style

Moignard, V., et al. “Characterization of Transcriptional Networks in Blood Stem and Progenitor Cells Using High-Throughput Single-Cell Gene Expression Analysis.” Nature Cell Biology, vol. 15, no. 4, 2013, pp. 363–72.

Chicago Style

Moignard, V, I MacAulay, G Swiers, F Buettner, J Schütte, F Calero-Nieto, S Kinston, et al. 2013. “Characterization of Transcriptional Networks in Blood Stem and Progenitor Cells Using High-Throughput Single-Cell Gene Expression Analysis.” Nature Cell Biology 15 (4): 363–72.
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Publisher copy:: 10.1038/ncb2709

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+ Moignard, V More by this author

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+ MacAulay, I More by this author

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+ Swiers, G More by this author

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+ Buettner, F More by this author

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+ Schütte, J More by this author

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Bibliographic Details

Journal:: Nature Cell Biology
Volume:: 15
Issue:: 4
Pages:: 363-372
Publication date:: 2013-04-01
DOI:: 10.1038/ncb2709
EISSN:: 1476-4679
ISSN:: 1465-7392

Item Description

Language:: English
Pubs id:: pubs:403169
UUID:: uuid:37d642dc-c678-4e83-b19e-2fa41d6aefd3
Local pid:: pubs:403169
Source identifiers:: 403169
Deposit date:: 2013-11-16

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Copyright date:: 2013

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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