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The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea.

Abstract:

INTRODUCTION: Germline mutations in E-cadherin (CDH1) have been reported in families with early onset, diffuse gastric cancer. More recently, mutations in CDH1 have been described in colorectal cancer cell lines. AIMS: We have investigated if germline mutations in CDH1 occur among different groups of Korean gastric and colorectal cancer patients, with and without a positive family history. METHODS: We studied 131 patients and 168 normal controls (88 Korean and 80 non-Korean). Patients were di...

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Publication status:
Published

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Publisher copy:
10.1136/gut.47.2.262

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Journal:
Gut
Volume:
47
Issue:
2
Pages:
262-267
Publication date:
2000-08-05
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
URN:
uuid:37d5a5d5-828f-44cd-ada1-73fe8b4a46bf
Source identifiers:
177998
Local pid:
pubs:177998

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