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Journal article

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter.

Abstract:

BACKGROUND: Macrophages (Mtheta) play a central role in the innate immune response and in the pathology of chronic inflammatory diseases. Macrophages treated with Th2-type cytokines such as Interleukin-4 (IL-4) and Interleukin-13 (IL-13) exhibit an altered phenotype and such alternatively activated macrophages are important in the pathology of diseases characterised by allergic inflammation including asthma and atopic dermatitis. The CC chemokine Thymus and Activation-Regulated Chemokine (TA...

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Publication status:
Published

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Publisher copy:
10.1186/1471-2199-7-45

Authors


Liddiard, K More by this author
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Journal:
BMC molecular biology
Volume:
7
Pages:
45
Publication date:
2006
DOI:
EISSN:
1471-2199
ISSN:
1471-2199
URN:
uuid:37cb4e88-25cc-47ed-b17c-3afafabd50c0
Source identifiers:
25151
Local pid:
pubs:25151

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