Journal article icon

Journal article

Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair

Abstract:

We deveiop a novel mathematical model for collagen deposition and alignment during dermal wound healing. We focus on the interactions between fibroblasts, modelled as discrete entities, and a continuous extracellular matrix composed of collagen and a fibrin based blood clot. There are four basic interactions assumed in the model: fibroblasts orient the collagen matrix, fibroblasts produce and degrade collagen and fibrin and the matrix directs the fibroblasts and determines the speed of the ce...

Expand abstract

Actions


Access Document


Files:

Authors


J. C. Dallon More by this author
J. A. Sherratt More by this author
P. K. Maini More by this author
M. Ferguson More by this author
Publication date:
2000
URN:
uuid:37c9d4bc-201e-4136-ba4f-3b0199d17562
Local pid:
oai:eprints.maths.ox.ac.uk:411

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP