- Abstract:
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We deveiop a novel mathematical model for collagen deposition and alignment during dermal wound healing. We focus on the interactions between fibroblasts, modelled as discrete entities, and a continuous extracellular matrix composed of collagen and a fibrin based blood clot. There are four basic interactions assumed in the model: fibroblasts orient the collagen matrix, fibroblasts produce and degrade collagen and fibrin and the matrix directs the fibroblasts and determines the speed of the ce...
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- Publication date:
- 2000
- URN:
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uuid:37c9d4bc-201e-4136-ba4f-3b0199d17562
- Local pid:
- oai:eprints.maths.ox.ac.uk:411
- Copyright date:
- 2000
Journal article
Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair
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