Cell-mediated immunity to a synthetic gliadin peptide resembling a sequence from adenovirus 12.

Journal article

Cell-mediated immunity to a synthetic peptide, which has a 12-residue sequence from A-gliadin analogous to part of an early-region protein (Elb) from adenovirus 12, was investigated in patients with coeliac disease, healthy subjects, and disease controls by means of an indirect leucocyte-migration-inhibition assay. Patients with coeliac disease being treated with a gluten-free diet showed a significantly greater response than healthy subjects (p less than 0.001) or patients with inflammatory ...

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Authors: Karagiannis, J; Priddle, J; Jewell, D

• Publication status: Published
• Journal: Lancet
• Volume: 1
• Issue: 8538
• Pages: 884-886
• Publication date: 1987-04-01
• DOI: 10.1016/s0140-6736(87)92859-5
• EISSN: 1474-547X
• ISSN: 0140-6736
• Language: English
• Keywords: Gliadin; Oncogene Proteins, Viral; Male; Celiac Disease; Aged; Leukocytes; Adult; Plant Proteins; Adenovirus Early Proteins; Middle Aged; Dose-Response Relationship, Immunologic; HLA Antigens; Peptide Fragments; Female; Humans; Cell Migration Inhibition