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Systematic literature review and meta-analysis of the efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: methodological challenges

Abstract:

There is no agreed standard method to assess the efficacy of anti-malarials for uncomplicated falciparum in pregnancy despite an increased risk of adverse outcomes for the mother and the fetus. The aim of this review is to present the currently available evidence from both observational and interventional cohort studies on anti-malarial efficacy in pregnancy and summarize the variability of assessment and reporting found in the review process.Efficacy methodology and assessment of artemisinin...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12936-017-2135-y

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
ORCID:
0000-0002-1667-9287
Gilder, ME More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
ORCID:
0000-0002-7951-0745
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Wellcome Trust More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
16
Issue:
488
Pages:
1-17
Publication date:
2017-12-13
Acceptance date:
2017-12-05
DOI:
ISSN:
1475-2875
Pubs id:
pubs:812258
URN:
uri:37bc5677-8a09-4bdb-916c-8b2e9697742b
UUID:
uuid:37bc5677-8a09-4bdb-916c-8b2e9697742b
Local pid:
pubs:812258

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