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Species specificity in the activation of Xer recombination at dif by FtsK.

Abstract:

In Escherichia coli, chromosome dimers are resolved to monomers by the addition of a single cross-over at a specific locus on the chromosome, dif. Recombination is performed by two tyrosine recombinases, XerC and XerD, and requires the action of an additional protein, FtsK. We show that Haemophilus influenzae FtsK activates recombination by H. influenzae XerCD at H. influenzae dif. However, it cannot activate recombination by E. coli XerCD. Reciprocally, E. coli FtsK cannot activate recombina...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Molecular microbiology
Volume:
49
Issue:
1
Pages:
241-249
Publication date:
2003-07-01
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
Source identifiers:
100014
Language:
English
Keywords:
Pubs id:
pubs:100014
UUID:
uuid:37b2aa7e-5a4b-473d-9ec4-082695034800
Local pid:
pubs:100014
Deposit date:
2012-12-19

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