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Neural correlates of visuospatial working memory in the 'at-risk mental state'.

Abstract:

BACKGROUND: Impaired spatial working memory (SWM) is a robust feature of schizophrenia and has been linked to the risk of developing psychosis in people with an at-risk mental state (ARMS). We used functional magnetic resonance imaging (fMRI) to examine the neural substrate of SWM in the ARMS and in patients who had just developed schizophrenia. METHOD: fMRI was used to study 17 patients with an ARMS, 10 patients with a first episode of psychosis and 15 age-matched healthy comparison subjects...

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Publisher copy:
10.1017/s0033291710000280

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Journal:
Psychological medicine
Volume:
40
Issue:
12
Pages:
1987-1999
Publication date:
2010-12-05
DOI:
EISSN:
1469-8978
ISSN:
0033-2917
URN:
uuid:379481a4-a54f-4744-b446-b42b4497e147
Source identifiers:
403431
Local pid:
pubs:403431

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