- Abstract:
-
Motor neurons are large, highly polarised cells with very long axons and a requirement for precise spatial and temporal gene expression. Neurodegenerative disorders characterised by selective motor neuron vulnerability include various forms of amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). A rapid expansion in knowledge on the pathophysiology of motor neuron degeneration has occurred in recent years, largely through the identification of genes leading to familial forms...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1017/s1462399410001523
-
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- Journal:
- Expert reviews in molecular medicine
- Volume:
- 12
- Pages:
- e21
- Publication date:
- 2010
- DOI:
- EISSN:
-
1462-3994
- ISSN:
-
1462-3994
- URN:
-
uuid:378dd133-66a1-4e98-89c5-9cedfc8a7e96
- Source identifiers:
-
241981
- Local pid:
- pubs:241981
- Copyright date:
- 2010
Journal article
The role of RNA processing in the pathogenesis of motor neuron degeneration.
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