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Journal article

A structure-based rationale for sialic acid independent host-cell entry of Sosuga virus

Abstract:

The bat-borne paramyxovirus, Sosuga virus (SosV), is one of many paramyxoviruses recently identified and classified within the newly established genus Pararubulavirus, family Paramyxoviridae The envelope surface of SosV presents a receptor-binding protein (RBP), SosV-RBP, which facilitates host-cell attachment and entry. Unlike closely related hemagglutinin neuraminidase RBPs from other genera of the Paramyxoviridae, SosV-RBP and other pararubulavirus RBPs lack many of the stringently conserv...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1073/pnas.1906717116

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
ORCID:
0000-0002-8066-8785
Publisher:
National Academy of Sciences Publisher's website
Journal:
Proceedings of the National Academy of Sciences Journal website
Volume:
116
Issue:
43
Pages:
21514-21520
Publication date:
2019-10-07
Acceptance date:
2019-09-09
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
Pmid:
31591233
Language:
English
Keywords:
Pubs id:
pubs:1062753
UUID:
uuid:378b9a69-1405-4d69-8b86-45df7fec5b63
Local pid:
pubs:1062753
Source identifiers:
1062753
Deposit date:
2019-11-14

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