Choreographing endo-lysosomal Ca2+ throughout the life of a phagosome

Journal article : Review

The emergence of endo-lysosomes as ubiquitous Ca²⁺ stores with their unique cohort of channels has resulted in their being implicated in a growing number of processes in an ever-increasing number of cell types. The architectural and regulatory constraints of these acidic Ca²⁺ stores distinguishes them from other larger Ca²⁺ sources such as the ER and influx across the plasma membrane. In view of recent advances in the understanding of the mod...

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Authors: Morgan, AJ; Davis, LC; Galione, A

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Elsevier Publisher's website
• Journal: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Journal website
• Volume: 1868
• Issue: 7
• Article number: 119040
• Publication date: 2021-04-17
• Acceptance date: 2021-04-07
• DOI: 10.1016/j.bbamcr.2021.119040
• EISSN: 1879-2596
• ISSN: 0167-4889
• Pmid: 33872669
• Language: English
• Keywords: calcium signaling; humans; FFR; calcium; transient receptor potential channels; endosomes; calcium channels; cell membrane; animals; NADP; phagosomes; phagocytosis; lysosomes
• Subtype: Review