Journal article icon

Journal article

Clinical radiobiology of proton therapy: modeling of RBE

Abstract:

Purpose:

To better estimate relative biological effectiveness (RBE) in therapeutic proton beams by using a modeled approach, in order to improve their clinical safety and effectiveness.

Introduction:

Concerns exist about the 1.1 RBE used in proton therapy, since it may lead to unintentional over- and under-dosage in patients and so lead to unexpected clinical outcomes. Late reacting normal tissues (with low a/b values), might be overdosed if RBE >1.1; very radiosensitive tumo... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

Actions


Access Document


Files:
Publisher copy:
10.1080/0284186x.2017.1343496

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Subgroup:
CRUK/MRC Ox Inst Radiation Oncology
Publisher:
Taylor and Francis Publisher's website
Journal:
Acta Oncologica Journal website
Volume:
56
Issue:
11
Pages:
1374–1378
Publication date:
2017-08-18
Acceptance date:
2017-06-09
DOI:
EISSN:
1651-226X
ISSN:
0284-186X
Pubs id:
pubs:724136
URN:
uri:377c7668-d5f0-4d98-8172-c4a673d8193e
UUID:
uuid:377c7668-d5f0-4d98-8172-c4a673d8193e
Local pid:
pubs:724136
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP