Journal article
Assembly and transport mechanism of tripartite drug efflux systems.
- Abstract:
-
Multidrug efflux (MDR) pumps remove a variety of compounds from the cell into the external environment. There are five different classes of MDR pumps in bacteria, and quite often a single bacterial species expresses multiple classes of pumps. Although under normal circumstances MDR pumps confer low-level intrinsic resistance to drugs, the presence of drugs and mutations in regulatory genes lead to high level expression of MDR pumps that can pose problems with therapeutic treatments. This revi...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.bbapap.2009.02.017
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Authors
Bibliographic Details
- Journal:
- Biochimica et biophysica acta
- Volume:
- 1794
- Issue:
- 5
- Pages:
- 817-825
- Publication date:
- 2009-05-01
- DOI:
- ISSN:
-
0006-3002
- Source identifiers:
-
155946
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:155946
- UUID:
-
uuid:377c1526-1d6c-45fd-979a-55911cfa0b63
- Local pid:
- pubs:155946
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2009
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