- Abstract:
-
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom high-density array of 46,939 PrCa cases and 27,910 controls of European ancestry with previously genotyped data of 32,255 PrCa cases and 33,202 controls of European ancestry. Our analysis identified 62 novel loci associated (P < 5.0 × 10−8) with PrCa and one locus significantly associated with early-on...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(x-zip-compressed, 15.4mb)
-
(pdf, 501.4kb)
-
- Publisher copy:
- 10.1038/s41588-018-0142-8
-
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- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Genetics Journal website
- Volume:
- 50
- Pages:
- 928–936
- Publication date:
- 2018-06-11
- Acceptance date:
- 2018-04-05
- DOI:
- EISSN:
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1546-1718
- ISSN:
-
1061-4036
- Pubs id:
-
pubs:800925
- URN:
-
uri:376b5ec0-7754-4e1b-ace8-9da421cd15fa
- UUID:
-
uuid:376b5ec0-7754-4e1b-ace8-9da421cd15fa
- Local pid:
- pubs:800925
- Copyright holder:
- Schumacher, et al
- Copyright date:
- 2018
- Notes:
- © Schumacher, et al 2018. This is the author accepted manuscript following peer review version of the article. The final version is available online from Springer Nature at: 10.1038/s41588-018-0142-8. For the full author and funding list see the article at: 10.1038/s41588-018-0142-8
Journal article
Prostate cancer meta-analysis of more than 140,000 men identifies 63 novel prostate cancer susceptibility loci
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