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Journal article

The role of matrix metalloproteinases in rheumatoid tendon disease.

Abstract:

In rheumatoid arthritis (RA) invasive tenosynovitis is associated with an increase in tendon rupture, although little is known about the mechanisms involved. We obtained specimens of noninvasive encapsulating tenosynovium, invasive tenosynovium, and wrist joint synovium from 28 rheumatoid patients. In vitro production of the matrix metalloproteinase (MMP) enzymes, MMP-8 and -9, and total collagenase activity were measured. Invasive tenosynovium produced highest levels of the collagenase MMP-8...

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Publication status:
Published

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Publisher copy:
10.1053/jhsu.2002.36516

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
The Journal of hand surgery
Volume:
27
Issue:
6
Pages:
1059-1064
Publication date:
2002-11-05
DOI:
EISSN:
1531-6564
ISSN:
0363-5023
URN:
uuid:3747207f-426f-4ad4-84c6-2ed1db7e296e
Source identifiers:
226759
Local pid:
pubs:226759

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