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Journal article

A randomized controlled trial investigating the effects of celecoxib in patients with localized prostate cancer.

Abstract:

UNLABELLED: Cyclooxygenase-2 (COX-2) is associated with tumour promotion, inhibition of apoptosis, angiogenesis and metastasis. Celecoxib, a selective COX-2 inhibitor was investigated, in patients with clinically localized prostate cancer using immunohistochemistry. PATIENTS AND METHODS: Patients with cT1-2 prostate cancer (n=45) were randomized to celecoxib 400mg b.d. or no treatment for four weeks prior to radical prostatectomy. Histological sections of preoperative biopsy and matched radi...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
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Journal:
Anticancer research
Volume:
29
Issue:
5
Pages:
1483-1488
Publication date:
2009-05-01
EISSN:
1791-7530
ISSN:
0250-7005
Source identifiers:
414534
Language:
English
Keywords:
Pubs id:
pubs:414534
UUID:
uuid:373e5967-5b35-4ef3-91e4-17236bb5646d
Local pid:
pubs:414534
Deposit date:
2013-11-16

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