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Thesis

The influence of lipid binding on the oligomeric state of membrane protein complexes

Abstract:

A large fraction of membrane proteins assemble into long-lived, non-covalent complexes, in a process called oligomerisation. Oligomerisation confers many benefits on membrane proteins, from increased thermal stability and access to a greater diversity of potential functions, to greater opportunities for cellular regulation. Despite this ubiquity and importance, membrane protein oligomerisation, and the role of the lipid environment in determining oligomeric state are poorly understood.

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Oxford college:
Hertford College
Role:
Depositor, Author

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Supervisor
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Grant:
Programme:
Life Sciences Interface Doctoral Training Centre
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English

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