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Journal article

Differential effect on myelination through abolition of activity dependent synaptic vesicle release or reduction of overall electrical activity of selected cortical projections in the mouse

Abstract:

Myelination of axons by oligodendrocytes in the central nervous system is crucial for fast, saltatory conduction of action potentials. As myelination is central for brain development and plasticity, and deficits are implicated in several neural disorders such as multiple sclerosis, major depressive disorder, bipolar disorder and schizophrenia, it is important to elucidate the underlying mechanisms regulating myelination. Numerous mechanisms have been proposed by which the communication betwee...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1111/joa.12974

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
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Publisher:
Wiley Publisher's website
Journal:
Journal of Anatomy Journal website
Publication date:
2019-03-22
Acceptance date:
2019-02-08
DOI:
EISSN:
1469-7580
ISSN:
0021-8782
Pubs id:
pubs:971983
URN:
uri:371cd73a-a97b-4031-b199-102e1d1b8edb
UUID:
uuid:371cd73a-a97b-4031-b199-102e1d1b8edb
Local pid:
pubs:971983

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