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Rate of change (modulation) of serum growth hormone concentrations is a more important factor in determining growth rate than duration of exposure.

Abstract:

OBJECTIVE: To determine whether duration of exposure to GH and/or rate of change of serum GH concentration are important factors in determining the growth rate of short children. DESIGN: An analysis of parameters of occupancy percentage and rate of change of serum GH concentration was performed as part of a prospective study investigating the relationship between growth and GH in childhood. PATIENTS: Sixty-four short prepubertal children (48 male, 16 female) aged between 4.7 and 11.9 years we...

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Publication status:
Published

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Authors


Hindmarsh, PC More by this author
Matthews, DR More by this author
Stratton, I More by this author
Pringle, PJ More by this author
Journal:
Clinical endocrinology
Volume:
36
Issue:
2
Pages:
165-170
Publication date:
1992-02-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:37160624-f12b-47ac-94fb-720327a914cc
Source identifiers:
72911
Local pid:
pubs:72911

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