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Assessment of cumulative evidence on genetic associations: interim guidelines.

Abstract:

Established guidelines for causal inference in epidemiological studies may be inappropriate for genetic associations. A consensus process was used to develop guidance criteria for assessing cumulative epidemiologic evidence in genetic associations. A proposed semi-quantitative index assigns three levels for the amount of evidence, extent of replication, and protection from bias, and also generates a composite assessment of 'strong', 'moderate' or 'weak' epidemiological credibility. In additio...

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Publication status:
Published

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Publisher copy:
10.1093/ije/dym159

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Journal:
International journal of epidemiology
Volume:
37
Issue:
1
Pages:
120-132
Publication date:
2008-02-05
DOI:
EISSN:
1464-3685
ISSN:
0300-5771
URN:
uuid:36f96b9b-1ab3-435a-be26-2abdf6557e19
Source identifiers:
27067
Local pid:
pubs:27067

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