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Gene expression studies to investigate disease mechanisms in rheumatoid arthritis: Does angiogenesis play a role?

Abstract:

Gene expression studies represent a new and challenging approach that allows molecular dissection of complex diseases such as rheumatoid arthritis (RA). Optimally, gene analysis should be conducted in isolated populations of cells so that the differential gene expression may be directly correlated with transcription of genes. RA fibroblasts constitute the majority of the expanding synovial cell mass in the RA joint, and alterations in their phenotype are likely to be important in the pathogen...

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Publisher copy:
10.2174/157339707782408991
Journal:
Current Rheumatology Reviews
Volume:
3
Issue:
4
Pages:
243-251
Publication date:
2007-11-01
DOI:
ISSN:
1573-3971
Language:
English
Pubs id:
pubs:231728
UUID:
uuid:36f5217c-5bde-4920-bf8f-dbdada2e2e91
Local pid:
pubs:231728
Source identifiers:
231728
Deposit date:
2013-11-16

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