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Neuroendocrine effects of sumatriptan.

Abstract:

The neuroendocrine effects of the 5-HT receptor agonist, sumatriptan (6 mg subcutaneously), were studied in 11 healthy male subjects using a placebo-controlled, cross-over design. Compared to placebo, sumatriptan significantly lowered levels of plasma prolactin but increased those of plasma growth hormone. There was no effect on plasma cortisol concentrations. The neuroendocrine effects of sumatriptan differ from those of previously described 5-HT-receptor agonists, and may be a consequence o...

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Publication status:
Published

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Publisher copy:
10.1007/bf02245240

Authors


Herdman, JR More by this author
Hockney, RE More by this author
Campling, GM More by this author
Journal:
Psychopharmacology
Volume:
113
Issue:
3-4
Pages:
561-564
Publication date:
1994-01-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:36f460ae-3bec-427f-aa44-a2dd915d90d3
Source identifiers:
186009
Local pid:
pubs:186009

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