- Abstract:
-
An open randomised trial was conducted to compare ceftazidime (120 mg/kg/day) with "conventional therapy" (chloramphenicol 100 mg/kg/day, doxycycline 4 mg/kg/day, trimethoprim 10 mg/kg/day, and sulphamethoxazole 50 mg/kg/day) in the treatment of severe melioidosis. A paired restricted sequential trial designed to detect a reduction in mortality from 80 to 40% in culture-positive patients surviving greater than 48 hours was stopped after 22 months. Of the 161 patients entered into the study, 6...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/s0140-6736(89)90768-x
-
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- Journal:
- Lancet
- Volume:
- 2
- Issue:
- 8665
- Pages:
- 697-701
- Publication date:
- 1989-09-05
- DOI:
- EISSN:
-
1474-547X
- ISSN:
-
0140-6736
- URN:
-
uuid:36eaca20-d7e8-446e-b39c-a85646fe485c
- Source identifiers:
-
43177
- Local pid:
- pubs:43177
- Language:
- English
- Keywords:
- Copyright date:
- 1989
Journal article
Halving of mortality of severe melioidosis by ceftazidime.
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