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Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo

Abstract:
Background
Single low-dose primaquine (SLDPQ) effectively blocks the transmission of Plasmodium falciparum malaria, but anxiety remains regarding its haemolytic potential in patients with glucose-6-phopshate dehydrogenase (G6PD) deficiency. We, therefore, examined the independent effects of several factors on haemoglobin (Hb) dynamics in falciparum-infected children with a particular interest in SLDPQ and G6PD status.
Methods
This randomised, dou... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12916-023-03105-0

Authors


Publisher:
BioMed Central
Journal:
BMC Medicine More from this journal
Volume:
21
Issue:
1
Article number:
397
Place of publication:
England
Publication date:
2023-10-20
Acceptance date:
2023-10-05
DOI:
EISSN:
1741-7015
Pmid:
37858129
Language:
English
Keywords:
Pubs id:
1546798
Local pid:
pubs:1546798
Deposit date:
2023-11-07

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