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Transcription occurs at a nucleoskeleton.

Abstract:

Native chromatin aggregates under isotonic conditions so it is generally studied using higher or lower salt concentrations. This has led to different interpretations of how transcription might occur. Studies using hypertonically-isolated preparations suggest that DNA functions in close association with a skeletal nuclear substructure, the matrix or cage, but such a structure is not usually seen under hypotonic conditions (e.g., in 'Miller-spreads'). Using a novel method for preparing chromati...

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Publication status:
Published

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Authors


Jackson, DA More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
The EMBO journal
Volume:
4
Issue:
4
Pages:
919-925
Publication date:
1985-04-05
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:36d17ff5-77a7-4bce-8aeb-d96b037afe38
Source identifiers:
13608
Local pid:
pubs:13608

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