Antibodies to SS-A/Ro-52kD and centromere in autoimmune liver disease: a clue to diagnosis and prognosis of primary biliary cirrhosis.

Journal article

BACKGROUND: Primary biliary cirrhosis (PBC) may be associated with various rheumatological disorders. AIM: To investigate the frequency and significance of 'rheumatological' antinuclear antibodies in the field of autoimmune chronic liver disease, with special regard to PBC. METHODS: We studied 105 patients with PBC, 162 autoimmune liver disease controls (type 1 and 2 autoimmune hepatitis, primary sclerosing cholangitis), 30 systemic lupus erythematosus and 50 blood donors. Sera were tested fo...

Expand abstract

Authors: Granito, A; Muratori, P; Muratori, L; Pappas, G; Cassani, F

• Publication status: Published
• Journal: Alimentary pharmacology and therapeutics
• Volume: 26
• Issue: 6
• Pages: 831-838
• Publication date: 2007-09-01
• DOI: 10.1111/j.1365-2036.2007.03433.x
• EISSN: 1365-2036
• ISSN: 0269-2813
• Language: English
• Keywords: Adult; Fluorescent Antibody Technique; Aged; Liver Cirrhosis, Biliary; Chronic Disease; Aged, 80 and over; Female; Middle Aged; Humans; Liver Diseases; Autoimmune Diseases; Antibodies, Antinuclear; Male; Prognosis