Cholangiocarcinoma in primary sclerosing cholangitis: risk factors and clinical presentation.

Journal article

BACKGROUND: Primary sclerosing cholangitis (PSC) confers a high risk of cholangiocarcinoma (CC) development. Since patients at risk of CC may be selected for early liver transplantation, it is a challenge to identify any predisposing factors. We compared the presentation and natural history of a large number of PSC patients with and without later CC development to identify features associated with risk of CC. METHODS: Clinical and laboratory data from presentation and follow-up were collected...

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Authors: Boberg, K; Bergquist, A; Mitchell, S; Pares, A; Rosina, F

• Publication status: Published
• Journal: Scandinavian journal of gastroenterology
• Volume: 37
• Issue: 10
• Pages: 1205-1211
• Publication date: 2002-10-01
• DOI: 10.1080/003655202760373434
• EISSN: 1502-7708
• ISSN: 0036-5521
• Language: English
• Keywords: Risk Factors; Outcome Assessment (Health Care); Follow-Up Studies; Female; Cholangitis, Sclerosing; Adult; Middle Aged; Bile Duct Neoplasms; Male; Time Factors; Odds Ratio; Humans; Bile Ducts, Intrahepatic; Survival Rate; Cholangiocarcinoma