Journal article
The effect of remifentanil on respiratory variability, evaluated with dynamic modeling.
- Abstract:
-
Opioid drugs disrupt signaling in the brain stem respiratory network affecting respiratory rhythm. We evaluated the influence of a steady-state infusion of a model opioid, remifentanil, on respiratory variability during spontaneous respiration in a group of 11 healthy human volunteers. We used dynamic linear and nonlinear models to examine the effects of remifentanil on both directions of the ventilatory loop, i.e., on the influence of natural variations in end-tidal carbon dioxide (Pet(CO(2)...
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- Publication status:
- Published
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- Publisher copy:
- 10.1152/japplphysiol.90769.2008
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Authors
Bibliographic Details
- Journal:
- Journal of applied physiology (Bethesda, Md. : 1985)
- Volume:
- 106
- Issue:
- 4
- Pages:
- 1038-1049
- Publication date:
- 2009-04-01
- DOI:
- EISSN:
-
1522-1601
- ISSN:
-
8750-7587
- Source identifiers:
-
243443
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:243443
- UUID:
-
uuid:36796c4e-ddb3-4c5f-a370-963078099257
- Local pid:
- pubs:243443
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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