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A strategy to home-in on polygenes influencing susceptibility to anxiety

Abstract:

Genetic influences on susceptibility to neurotic disorders appear to consist of additive polygenes, with collective heritability of 30-50 per cent, determining comorbidity between specific disorders rather than the latter directly. Such susceptibility can be measured by questionnaire, e.g. the Eysenck Neuroticism (N) scale. N scores show a normally distributed variation across the population, with elevated values but no step change in clinical groups. Recent developments in allying the method...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Dawson, GR More by this author
Fulker, DW More by this author
Volume:
14
Issue:
S1
Pages:
S3-S10
Publication date:
1999-12-05
DOI:
EISSN:
1099-1077
ISSN:
0885-6222
URN:
uuid:365bbd7c-9f5d-43ae-9275-4841a9bd1cf1
Source identifiers:
6156
Local pid:
pubs:6156

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