Non-coding RNA in transcription initiation.

Journal article

Diverse classes of non-coding RNAs, including snRNAs (small nuclear RNAs), play fundamental regulatory roles in gene expression. For example, 7SK RNA and the components of the splicing apparatus U1-U6 snRNAs are implicated in the regulation of transcriptional elongation. The first evidence for the involvement of RNA in the regulation of transcriptional initiation is now emerging. TFIIH (transcription factor IIH), a general transcription initiation factor, appears to associate specifically wit...

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Authors: O'Gorman, W; Kwek, K; Thomas, B; Akoulitchev, A

• Publication status: Published
• Journal: Biochemical Society symposium
• Issue: 73
• Pages: 131-140
• Publication date: 2006-01-01
• EISSN: 1744-1439
• ISSN: 0067-8694
• Language: English
• Keywords: RNA Polymerase II; RNA Processing, Post-Transcriptional; RNA, Untranslated; Transcription Factor TFIIH; Transcription, Genetic; RNA Splicing; Models, Biological; RNA, Small Nuclear