Journal article
Nested Russian doll-like genetic mobility drives rapid dissemination of the carbapenem resistance gene blaKPC
- Abstract:
-
The recent widespread emergence of carbapenem resistance in Enterobacteriaceae is a major public health concern, as carbapenems are a therapy of last resort in this family of common bacterial pathogens. Resistance genes can mobilize via various mechanisms including conjugation and transposition, however the importance of this mobility in short-term evolution, such as within nosocomial outbreaks, is currently unknown. Using a combination of short- and long-read whole genome sequencing of 281 b...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
+ Royal Society
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Funding agency for:
Wilson, D
Grant:
Sir Henry Dale Fellowship 101237/Z/13/Z
+ Wellcome Trust
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Funding agency for:
Stoesser, N
Wilson, D
Grant:
Research Fellowship
Sir Henry Dale Fellowship 101237/Z/13/Z
Health Innovation Challenge Fund WT098615/Z/12/Z
National Institute for Health Research
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Bibliographic Details
- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Antimicrobial Agents and Chemotherapy Journal website
- Publication date:
- 2016-05-23
- Acceptance date:
- 2016-04-03
- DOI:
- EISSN:
-
1098-6596
- ISSN:
-
0066-4804
Item Description
- Pubs id:
-
pubs:613088
- UUID:
-
uuid:3651d24e-6612-4948-b975-437c440b1787
- Local pid:
- pubs:613088
- Source identifiers:
-
613088
- Deposit date:
- 2016-04-04
Terms of use
- Copyright holder:
- Sheppard et al
- Copyright date:
- 2016
- Notes:
- © 2016 Sheppard et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
- Licence:
- CC Attribution (CC BY)
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