Conference item
Molecular basis of human natural killer cell recognition of HLA-E (human leucocyte antigen-E) and its relevance to clearance of pathogen-infected and tumour cells.
- Abstract:
-
HLA-E (human leucocyte antigen-E) is a conserved class I major histocompatibility molecule which has only limited polymorphism. It binds to the leader peptide derived from the polymorphic classical major histocompatibility molecules HLA-A, HLA-B and HLA-C. This peptide binding is highly specific and stabilizes the HLA-E protein, allowing it to migrate to the cell surface. A functioning TAP (transporter associated with antigen processing) molecule is required to transport these peptides into t...
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- Publication status:
- Published
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- Publisher copy:
- 10.1042/cs19990334
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Bibliographic Details
- Journal:
- Clinical science (London, England : 1979)
- Volume:
- 99
- Issue:
- 1
- Pages:
- 9-17
- Publication date:
- 2000-07-01
- Event title:
- Meeting of the Medical-Research-Society
- DOI:
- EISSN:
-
1470-8736
- ISSN:
-
0143-5221
- Source identifiers:
-
19508
Item Description
- Keywords:
- Pubs id:
-
pubs:19508
- UUID:
-
uuid:3637760a-09b3-461a-a457-e5197a780dbe
- Local pid:
- pubs:19508
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
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