Thesis
Investigating the role of SET1A and SET1B in the regulation of gene expression
- Abstract:
-
The development of complex multicellular organisms relies on the precise spatiotemporal control of gene expression. The post-translational modification of histone proteins within chromatin has emerged as an important mechanism by which the regulation of gene expression can be achieved. One such histone modification, H3K4me3, is intrinsically linked to transcriptional activity; levels of H3K4me3 at gene promoters are positively correlated with gene expression and numerous H3K4me3 ‘reader’ p...
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Funding
+ Wellcome Trust
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Funder identifier:
http://dx.doi.org/10.13039/100010269
Grant:
203829/Z/16/A
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Deposit date:
- 2021-11-16
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Terms of use
- Copyright holder:
- Hughes, AL
- Copyright date:
- 2021
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