Journal article icon

Journal article

Cellular function in multicellular system for hormone-secretion: electrophysiological aspect of studies on alpha-, beta- and delta-cells of the pancreatic islet.

Abstract:

We review a new method to explore the cellular functions in multicellular system by application of the perforated patch-clamp technique to intact pancreatic islet of Langerhans. Using this approach, the integrity of the islet is preserved and intercellular communication via gap junctions and paracrine processes are maintained. By using low-resistance patch electrodes, rapid current responses can be monitored under voltage-clamp control. We have applied this methodology to answer questions not...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Journal:
Neuroscience research
Volume:
42
Issue:
2
Pages:
79-90
Publication date:
2002-02-05
DOI:
EISSN:
1872-8111
ISSN:
0168-0102
URN:
uuid:36160195-cf28-45b9-b2dc-26761f6e22f2
Source identifiers:
15706
Local pid:
pubs:15706

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP