Epidemiological studies of large resistance plasmids in Haemophilus.

Journal article

The distribution of large conjugative Haemophilus influenzae plasmids in the nasopharyngeal haemophili of a group of people and in a large collection of 541 H. influenzae type b (Hib) isolates was studied. A newly developed PCR-based assay was used to detect the plasmids. The target sequences were chosen from sequence analysis of part of p1056, a large multiresistance plasmid isolated from a clinical Hib isolate, 1056. Fifty-nine per cent of people were found to carry beta-lactamase-positive ...

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Authors: Leaves, N; Dimopoulou, I; Hayes, I; Kerridge, S; Falla, T

• Publication status: Published
• Journal: Journal of antimicrobial chemotherapy
• Volume: 45
• Issue: 5
• Pages: 599-604
• Publication date: 2000-05-01
• DOI: 10.1093/jac/45.5.599
• EISSN: 1460-2091
• ISSN: 0305-7453
• Language: English
• Keywords: Ampicillin Resistance; Plasmids; Anti-Bacterial Agents; Child; beta-Lactamases; Adult; Nasopharynx; Microbial Sensitivity Tests; Tetracycline Resistance; Haemophilus influenzae; Carrier State; Polymerase Chain Reaction; Humans; Haemophilus Infections