Journal article
Highly enantioselective rhodium-catalyzed cross-coupling of boronic acids and racemic allyl halides
- Abstract:
-
Although Csp2-Csp2 Suzuki-Miyaura couplings (SMCs) are widely used in small-molecule synthesis, related methods that allow the incorporation of Csp3-hybridized coupling partners, particularly in an asymmetric manner, are less developed. This protocol describes catalytic asymmetric SMC reactions that provide access to enantiomerically enriched cyclic allylic products. The method couples racemic allyl halide starting materials with sp2-hybridized boronic acid derivatives and is compatible with ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Protocols Journal website
- Volume:
- 14
- Pages:
- 2972–2985
- Publication date:
- 2019-09-20
- Acceptance date:
- 2019-06-06
- DOI:
- EISSN:
-
1750-2799
- ISSN:
-
1754-2189
- Pmid:
-
31541227
- Source identifiers:
-
1056038
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1056038
- UUID:
-
uuid:35c95a4c-bb76-4b90-b37e-1f87bebdba83
- Local pid:
- pubs:1056038
- Deposit date:
- 2019-09-30
Terms of use
- Copyright date:
- 2019
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