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The effect of antibiotic exposure and specimen volume on the detection of bacterial pathogens in children with pneumonia

Abstract:

Background

Antibiotic exposure and specimen volume are known to affect pathogen detection by culture. Here we assess their effects on bacterial pathogen detection by both culture and polymerase chain reaction (PCR) in children.

Methods

PERCH (Pneumonia Etiology Research for Child Health) is a case-control study of pneumonia in children aged 1–59 months investigating pathogens in blood, nasopharyngeal/oropharyngeal (NP/OP) swabs, and induced sputum by culture and P...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/cid/cix101

Authors


Driscoll, AJ More by this author
Deloria Knoll, M More by this author
Hammitt, LL More by this author
Baggett, HC More by this author
Brooks, WA More by this author
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Bill and Melinda Gates Foundation More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Clinical Infectious Diseases Journal website
Volume:
64
Issue:
suppl_3
Pages:
S368-S377
Publication date:
2017-05-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Pubs id:
pubs:827525
URN:
uri:35b3c641-a3d1-46c6-901f-a811b2c4c88b
UUID:
uuid:35b3c641-a3d1-46c6-901f-a811b2c4c88b
Local pid:
pubs:827525

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