Journal article icon

Journal article

In vivo imaging of muscarinic receptors in the aging female brain with (R,R)[123I]-I-QNB and single photon emission tomography.

Abstract:

The effect of age on brain muscarinic receptor density is unclear. Some in vivo neuroimaging studies have reported a large age-related reduction in muscarinic receptor density; however, others have reported increases or no change. The variability in these results most likely arises because of the heterogeneity of the populations studied, differences in quantification methods employed, and a paucity of subtype selective ligands. Thus, we used the m(1)/m(4) selective probe (R,R)[(123)I]-I-QNB t...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.exger.2004.10.002

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Travis, MJ More by this author
Erlandsson, K More by this author
Waddington, W More by this author
Expand authors...
Journal:
Experimental gerontology
Volume:
40
Issue:
3
Pages:
137-145
Publication date:
2005-03-05
DOI:
EISSN:
1873-6815
ISSN:
0531-5565
URN:
uuid:35b1a7c6-1ee0-4a2c-8980-8e71effdba64
Source identifiers:
139489
Local pid:
pubs:139489

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP