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Journal article

Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101.

Abstract:

HLA-B*51 alleles are reported to be associated with slow disease progression to AIDS, but the mechanism underlying this association is still unclear. In the present study, we analyzed the effect of HLA-B*5101 on clinical outcome for Japanese hemophiliacs who had been infected with HIV-1 before 1985 and had been recruited in 1998 for this study. HLA-B*5101(+) hemophiliacs exhibited significantly slow progression. The analysis of HLA-B*5101-restricted HIV-1-specific cytotoxic T-lymphocyte (CTL)...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.00171-10

Authors


Kawashima, Y More by this author
Gatanaga, H More by this author
Fujiwara, M More by this author
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Journal:
Journal of virology
Volume:
84
Issue:
14
Pages:
7151-7160
Publication date:
2010-07-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:35aa6d96-19a7-4cf9-9df4-7212d759e7ee
Source identifiers:
191008
Local pid:
pubs:191008

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