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Atrial natriuretic peptides inhibit the release of corticotrophin-releasing factor-41 from the rat hypothalamus in vitro.

Abstract:

Atrial natriuretic peptide, ANP(99-126), is derived from cardiac atrial tissue and has potent effects on salt and water homeostasis, including the inhibition of aldosterone and vasopressin release. Recent studies have also suggested that it may suppress the pituitary-adrenal axis. In addition, N-truncated forms of ANP, such as ANP(103-126), have been identified within the central nervous system, with a prominent hypothalamic localization in the paraventricular nucleus. We have therefore inves...

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Publication status:
Published

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Publisher copy:
10.1677/joe.0.1260223

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
Journal:
The Journal of endocrinology
Volume:
126
Issue:
2
Pages:
223-228
Publication date:
1990-08-05
DOI:
EISSN:
1479-6805
ISSN:
0022-0795
URN:
uuid:3570fbfb-f8c6-4d43-b7ad-e2c10855d65a
Source identifiers:
138250
Local pid:
pubs:138250

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