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Thymidine phosphorylase expression in normal, hyperplastic and neoplastic prostates: correlation with tumour associated macrophages, infiltrating lymphocytes, and angiogenesis.

Abstract:

Thymidine phosphorylase is an angiogenic factor primarily expressed by cancer cells, stromal cells and tumour-associated macrophages in many human malignancies. These different types of thymidine phosphorylase-expressing cells, however, may have a distinct place in the angiogenic process, and this question was addressed in the present study. A series of 20 normal/hyperplastic prostate glands and 60 prostate carcinomas was investigated by immunohistochemistry, using specific antibodies for thy...

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Publisher copy:
10.1038/sj.bjc.6600281

Authors


Sivridis, E More by this author
Giatromanolaki, A More by this author
Papadopoulos, I More by this author
Gatter, KC More by this author
Harris, AL More by this author
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Journal:
British journal of cancer
Volume:
86
Issue:
9
Pages:
1465-1471
Publication date:
2002-05-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:3545e920-0c5a-4df1-a93c-f08907bae63a
Source identifiers:
119165
Local pid:
pubs:119165

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